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Cancer treatments significantly elevate OS through multiple mechanisms: chemotherapeutic agents, particularly alkylating agents and platinum compounds, generate excessive ROS directly damaging sperm DNA and membranes (87, 88), while radiation therapy induces both acute and chronic OS states in testicular tissue, leading to prolonged spermatogenic dysfunction (95)

Management: Nerve blocks, physical therapy, and medications to alleviate nerve pain

Cysteine is sulfur donor for the synthesis of methionine, the major other sulfur-containing amino acid present in plants

Cellular thiols and redox-regulated signal transduction