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The gut-brain axis is real, and gut inflammation does correlate with depression and anxiety

Moreover, recent developments extend AIs role to customizing treatment strategies based on inflammatory markers, which are pivotal in managing chronic infections and systemic diseases [239]

Neurology 2004;63:2104-10.ArticlePubMed 31

What underpins progression at the tissue, cellular and molecular levels is still unknown, but taken together, emerging data strongly point to an underlying chronic cytodegenerative process starting early and operating largely independently of overt inflammation